血管緊張素Ⅱ對大鼠胰島β細胞形態功能的影響

血管緊張素Ⅱ對大鼠胰島β細胞形態功能的影響

作者：劉萍，何嵐，王毅，李建寧，葉楓，劉治全
【關鍵詞】 血管緊張素Ⅱ；鹽；胰島β細胞；高血壓;大鼠
　　Effects of angiotensin II on morphology and function of islets βcells in rats
　　【Abstract】 AIM: To study the effects of angiotensin II (AngⅡ) on the function and morphology of islets βcells. METHODS: The SD rats accepted AngⅡ by hypodermic injection with the osmotic minipump for 2 weeks. Hereafter, they were fed with a normal (8 g/L NaCl) or highsalt (40 g/L NaCl) diet respectively. The following indexes, including blood pressure, fasting blood glucose, insulin and the morphology of islets βcells were observed. RESULTS: The blood pressure of rats was significantly elevated 2 weeks after accepting AngⅡ via chronic hypodermic injection; at the end of 4 weeks, compared with control group, the blood pressure was increased unceasingly and markedly in the rat with AngⅡ infusions; meanwhile, the areas of islets βcells in the rats of highsalt diet became larger than those of control group (P

【血管緊張素Ⅱ對大鼠胰島β細胞形態功能的影響】相關文章：

吡格列酮對代謝綜合征患者血管內皮細胞功能的影響03-30

血管緊張素Ⅱ受體拮抗劑對高血壓病患者左室重構的影響03-06

振動刺激對廢用性肌萎縮大鼠肌纖維形態結構的影響03-03

淺論川芎嗪對內皮祖細胞的功能影響03-08

談石杉堿甲對老年大鼠腹部手術術后認知功能的影響03-19

電針和半夏瀉心湯對功能性消化不良大鼠胃動素的影響03-03

羧基肽酶-H抗體與LADA患者胰島功能關系03-08

模擬失重對成骨細胞整合素亞單位表達的影響12-04

探討體外培養的大鼠松果體細胞分泌的松果體素在持續黑暗的環境下03-03

超短波對大鼠坐骨神經損傷后血管內皮生長因子表達的影響03-08